COX IV Monoclonal Antibody (6C8) Size: 50μL, 100μL Catalogue Numbers: RA10526-50, RA10526-100 Citations, Manuals and MSDS Available upon request. Background: cytochrome c oxidase subunit 4I1 (COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol. Storage Instructions: -20°C/1 year Applications: WB; IHC-p; IF/ICC; Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 1327 Protein MW (KDa): 15 SWISS: P13073 Source: Mouse Research Use Only