Product Description

COX1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23709-50, RA23709-100

Citations, Manuals and MSDS Available upon request.

Background: prostaglandin-endoperoxide synthase 1 (PTGS1) Homo sapiens This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:1000

Alternative Names: PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1; YM3223

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 5742

Protein MW (KDa): 70

SWISS: P23219

Source: Rabbit

Research Use Only