COX11 rabbit pAb - ES4781

COX11 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4781-50, ES4781-100

Citations, Manuals and MSDS Available upon request.

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu (B) and magnesium centers of COX. This human protein is predicted to c

Alternate Name: COX11; Cytochrome c oxidase assembly protein COX11; mitochondrial

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human COX11. AA range:51-100

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 31kD

Human Gene ID: 1353

Human SWISS Prot NO: Q9Y6N1

Subcellular Location: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.

Research Use Only