COX15 Polyclonal Antibody
Catalogue Numbers: BS61079-50, BS61079-100
Sizes: 50µl, 100µl
Alternative Name: Cytochrome c oxidase assembly protein COX15 homolog; COX15
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q7KZN9
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: COX15 polyclonal antibody detects endogenous levels of COX15 protein.
Bioworld Molecular Weight: ~ 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of COX15 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human COX15.
Conjugate: Unconjugated
Modification: Unmodified