COX4 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23718-50, RA23718-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: cytochrome c oxidase subunit 4I1 (COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IHC-p, IF (paraffin section) Alternate Names: COX4I1, COX4, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1 Clonality: Polyclonal Dilution: WB: 1:1000 IHC: 1:500-1000 Molecular Weight: 15 Protein Molecular Weight (kDa): 15 Storage: -20°C/1 year Human Gene ID: 1327 Human SwissProt Number: P13073 Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol. Research Use Only