Product Description

COX7A2/3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67060-50, BS67060-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and mμltiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regμlation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing resμlts in mμltiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: COX7A2P2, COX7A3, COX7AL2, COX7AP2, Putative cytochrome c oxidase subunit 7A3 mitochondrial, Cytochrome c oxidase subunit VIIa 3, COX7A2, COX7AL, Cytochrome c oxidase subunit 7A2 mitochondrial, Cytochrome c oxidase subunit VIIa-liver/heart, Cytochrome c oxidase subunit VIIa-L, Cytochrome c oxidase subunit VIIaL

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human COX7A2/3. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IH (1/100 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of COX7A2/3 protein.

Molecular Weight: ~ 12 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60397, P14406

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only