Product Description

COXII Polyclonal Antibody

Catalogue Numbers: BS1653-50, BS1653-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q7JCZ1

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs .

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: COXII polyclonal antibody detects endogenous levels of COXII protein.

Extra Notes: Western blot (WB) analysis of COXII polyclonal antibody at 1:1000 dilution
Lane1:HepG-2 whole cell lysate(50μg)
Lane2:The muscle tissue lysate of Mouse(33μg)

Bioworld Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Cytochrome c oxidase polypeptide 2; Cytochrome c oxidase subunit 2; Cytochrome c oxidase subunit II; Cytochrome oxidase subunit 2; mt-Co2; Co2; COII; COX2; Cox2; COXII

Immunogen: A synthetic peptide corresponding to amino acids 49-63 of Mouse COXII.

Conjugate: Unconjugated

Modification: Unmodified