Product Description

CPB2 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalogue Numbers: BS65256-50, BS65256-100

Sizes: 50µl, 100µl

Swiss-Prot: Q96IY4

Host: Rabbit

Reactivity: Human

Applications: WB,ELISA

Background: carboxypeptidase B2(CPB2) Homo sapiens Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: TAFI Polyclonal Antibody detects endogenous levels of TAFI protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of lysates from HepG2 cells, using CPB2 Antibody. The lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from K562 cells using CPB2 antibody.

Bioworld Molecular Weight: ~ 48 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: CPB2; Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI

Immunogen: The antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370

Conjugate: Unconjugated

Modification: Unmodified