Product Description

CPD Polyclonal Antibody

Catalogue Numbers: BS60812-50, BS60812-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75976

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. CPD (carboxypeptidase D), also known as GP180 or metallocarboxypeptidase D, is a 1,380 amino acid single-pass type I membrane protein that belongs to the peptidase M14 family. CPD binds two zinc ions per subunit and contains three carboxypeptidase-like domains. CPD causes the release of C-terminal arganine and lysine from polypeptides. Highest expression of CPD is found in pancreas, hepatoma cells and placenta, with lower levels in heart, skeletal muscle and colon carcinoma. Mammalian CPD is a homolog of the duck hepatitis B virus-binding protein gp180.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CABIN1 polyclonal antibody detects endogenous levels of CABIN1 protein.

Extra Notes: Western blot (WB) analysis of CPD pAb at 1:500 dilution
Lane1:U-87MG whole cell lysate(40ug)
Lane2:SGC7901 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 200 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Carboxypeptidase D; Metallocarboxypeptidase D; gp180; CPD

Immunogen: A synthetic peptide corresponding to residues in Human CPD.

Conjugate: Unconjugated

Modification: Unmodified