Product Description

CPEB3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS72589-50, BS72589-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimμlated state but, following neuronal stimμlation, acts as a translational activator (By similarity. In contrast to CPEB1, does not bind to the cytoplasmic polyadenylation element (CPE, a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure (By similarity. Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity. In the basal state, binds to the mRNA 3'-UTR of the glutamate receptors GRIA2/GLUR2 mRNA and negatively regμlates their translation (By similarity. Also represses the translation of DLG4, GRIN1, GRIN2A and GRIN2B (By similarity. When activated, acts as a translational activator of GRIA1 and GRIA2 (By similarity.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: CPEB3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human CPEB3(NP_055727.3).

Dilution: WB, 1:200 - 1:2000 IHC, 1:50 - 1:200 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 75kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NE35

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only