CPI-17 Polyclonal Antibody - BT-AP02181

CPI-17 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02181-20, BT-AP02181-50, BT-AP02181-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A) belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for PPP1R14A.

Research Areas: Signal Transduction

Target Protein: PPP1R14A

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CPI-17 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 16693

UniProt Accession: Human: Q96A00; Mouse: Q91VC7; Rat: Q99MC0

Synonyms: PPP1R14A; CPI17; PPP1INL; Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17

GeneID: Human: 94274; Mouse: 68458; Rat: 114004

Research Use Only