Product Description

CPSF3L Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6946-50, BS6946-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a mμlti-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. This interaction is facilitated by phosphorylation of serine-7 on Pol II. CPSF3L (Cleavage and polyadenylation-specific factor 3-like protein), also known as Integrator complex subunit 11 (INTS11), is a 600 amino acid protein that is a component of the integrator complex and is expressed as three isoforms.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: Integrator complex subunit 11, Int11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68, CPSF3L, INTS11, RC68

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human CPSF3L.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CPSF3L polyclonal antibody detects endogenous levels of CPSF3L protein.

Molecular Weight: ~ 68 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q5TA45

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only