CREB-1 Monoclonal Antibody (4B4) - BT-MCA0383

CREB-1 Monoclonal Antibody (4B4)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0383-20, BT-MCA0383-50, BT-MCA0383-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Research Areas: Epigenetics and nuclear signaling; Immunology

Target Protein: CREB1

Applications: WB, IHC-p, IF

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Cyclic AMP-responsive element-binding protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P16220; Mouse: Q01147

Synonyms: CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1

GeneID: Human: 1385

Research Use Only