CREM rabbit pAb - ES4813

CREM rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4813-50, ES4813-100

Citations, Manuals and MSDS Available upon request.

Background: cAMP responsive element modulator (CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008],

Alternate Name: CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 34kD

Human Gene ID: 1390

Human SWISS Prot NO: Q03060

Subcellular Location: Nucleus.; [Isoform 6]: Cytoplasm. Nucleus.

Research Use Only