Product Description

CRLF2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31827-50, RA31827-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cytokine receptor-like factor 2 (CRLF2) Homo sapiens This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 40

Protein Molecular Weight (kDa): 40

Storage: -20°C/1 year

Human Gene ID: 64109

Human SwissProt Number: Q9HC73

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only