Product Description

CROCC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31831-50, RA31831-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis., PTM:Phosphorylated by NEK2 which may regulate its association with centrosomes. Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the rootletin family., subcellular location:In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase., subunit:Homopolymer. Interacts with KLC3, NEK2 and the N-terminus of CEP250.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 221

Protein Molecular Weight (kDa): 221

Storage: -20°C/1 year

Human Gene ID: 9696

Human SwissProt Number: Q5TZA2

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only