Crystallin-αC rabbit pAb - ES20776

Crystallin-αC rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20776-50, ES20776-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Alternate Name: HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22

Source: Rabbit

Applications: WB

Dilution: WB: 1:500-1000

Reactivity: Human

Immunogen: Recombinant Protein of Crystallin-αC

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 22kD

Human Gene ID: 26353

Human SWISS Prot NO: Q9UJY1

Subcellular Location: Cytoplasm. Nucleus. Translocates to nuclear foci during heat shock.

Research Use Only