CSF2RA Polyclonal Antibody
Catalogue Numbers: BS60920-50, BS60920-100
Sizes: 50µl, 100µl
Alternative Name: Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CDw116; CD116; CSF2RA; CSF2R; CSF2RY
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P15509
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β-subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit. Although neither the murine nor the human β subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CSF2RA polyclonal antibody detects endogenous levels of CSF2RA protein.
Bioworld Molecular Weight: ~ 46 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of CSF2RA polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human CSF2RA.
Conjugate: Unconjugated
Modification: Unmodified