Product Description

Csk Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11022-50, RA11022-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases., PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 SH3 domain., subcellular location:Mainly cytoplasmic, also present in lipid rafts., subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1., tissue specificity:Expressed in lung and macrophages.,

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Applications: WB, IF/ICC, FCM, ELISA

Alternate Names: CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL

Clonality: Monoclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Human Gene ID: 1445

Research Use Only