Product Description

Csk (N63) Polyclonal Antibody

Catalogue Numbers:BS2275-50, BS2275-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P41240

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC, IF

All Applications: IHC: 1:50~1:200
IF: 1:50~1:200

Background: C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 50 kDa

Specificity: Csk (N63) polyclonal antibody detects endogenous levels of Csk protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK

Immunogen: Synthetic peptide, corresponding to amino acids N-terminus of Human Csk.

Conjugate: Unconjugated

Modification: Unmodified