Product Description

Csk (phospho Ser364) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23837-50, RA23837-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases., PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 SH3 domain., subcellular location:Mainly cytoplasmic, also present in lipid rafts., subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1., tissue specificity:Expressed in lung and macrophages.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 55

Protein Molecular Weight (kDa): 55

Storage: -20°C/1 year

Human Gene ID: 1445

Human SwissProt Number: P41240

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only