CSK22 rabbit pAb - ES10810

CSK22 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10810-50, ES10810-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily., similarity:Contains 1 protein kinase domain., subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 1459

Human SWISS Prot NO: P19784

Subcellular Location: Nucleus. Cytoplasm. Interaction with SIRT6 prevents translocation into the nucleus.

Research Use Only