Product Description

CtBP1/2 (Phospho Ser158/164) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23868-50, RA23868-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change., function:Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity., PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA)., PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4., PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation., similarity:Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family., subunit:Interacts with the C-terminus of adenovirus E1A protein, ELK3 and CTIP via their consensus motif P-X-[DNS]-L-[STVA]. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with FOXP2, HDAC4, HDAC5 and HDAC9. Interacts with GLIS2 but not GLIS1 or GLIS3 (By similarity). Interacts with FOXP1, HIPK2, PNN and NRIP1. Interacts with ZFHX1B and WIZ. Interacts with Epstein-Barr virus EBNA3 and EBNA6.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: C-terminal-binding protein 1 (CtBP1;EC 1.1.1.-)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 48

Protein Molecular Weight (kDa): 48

Storage: -20°C/1 year

Human Gene ID: 1487

Human SwissProt Number: Q13363/P56545

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only