CTDP1 rabbit pAb - ES17188

CTDP1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES17188-50, ES17188-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],

Alternate Name: RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human CTDP1 AA range: 73-123

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 105kD

Human Gene ID: 9150

Human SWISS Prot NO: Q9Y5B0

Subcellular Location: Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively.

Research Use Only