Product Description

CTGF Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90340-50, BS90340-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P29279(Human) P29268(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC IHC

All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200

Background: Connective tissue growth factor (CTGF, also known as hypertrophic chondrocyte-specific gene product 24 or Hcs24), is a member of the CCN family of immediate early proteins, which are involved in cell proliferation, migration and matrix production. CTGF is a cysteine-rich peptide that is secreted by endothelial cells, fibroblasts, smooth muscle cells and myofibroblasts. Its expression is increased in various human and animal fibrotic diseases. Specifically, CTGF has been observed to be strongly upregulated in human proliferative and fibrogenic renal disease. In addition, CTGF is a growth factor for vascular smooth muscle cells (VSMC) and may play a similar role in promoting VSMC growth and migration in vitro.

Purification and Purity: Protein affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: CTGF polyclonal antibody detects endogenous levels of CTGF protein.

Bioworld Molecular Weight: 38 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CTGF on mouse smooth muscle tissue lysate using anti-CTGF antibody at 1/500 dilution., ICC staining CTGF in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: IBP-8, IGF-binding protein 8, IGFBP-8, CTGF, CCN2, HCS24, IGFBP8, CCN 2, CCN family member 2, CCN2, Connective tissue growth factor, Ctgf, CTGF, Hcs 24, Hcs24, Hypertrophic chondrocyte specific protein 24, Hypertrophic chondrocyte-specific gene product 24, Hypertrophic chondrocyte-specific protein 24 antibody IBP-8, IGF-binding protein 8, IGFBP-8, IGFBP8, Insulin like Growth Factor Binding Protein 8, Insulin-like growth factor-binding protein 8, MGC102839, NOV 2, NOV2,

Immunogen: Recombinant protein with human CTGF aa 150-300.

Conjugate: Unconjugated

Modification: Unmodified