Product Description

CTNNB1 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4261-25, MB4261-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regμlating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medμlloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

Category: Primary Antibody

Reactivity: Human, Dog, Rat, Monkey, Mouse

Host: Mouse

Applications: FC, IF, WB

Alternate Names: armadillo, CTNNB, MRD19

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.

Dilution: WB 1:500~2000, IF 1:100, FLOW 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: 85.3 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P35222

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only