CTPS rabbit pAb - ES2070

CTPS rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2070-50, ES2070-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Alternate Name: CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 67kD

Human Gene ID: 1503

Human SWISS Prot NO: P17812

Subcellular Location: Cytoplasm, cytosol. Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282). Co-localizes with TNK2 in the cytosolic filaments (By similarity).

Research Use Only