CUTA Polyclonal Antibody - E-AB-18633

CUTA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18633-60, E-AB-18633-120, E-AB-18633-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CUTA

Target Synonym: Acetylcholinesterase Associated Protein; Acetylcholinesterase-associated protein; ACHAP; Brain acetylcholinesterase putative membrane anchor; C6ORF82; cutA; CutA Divalent Cation Tolerance Homolog ; cutA divalent cation tolerance homolog (E. coli); CUTA; CutA1; divalent cation tolerant protein CUTA; MGC111154; OTTHUMP00000039621; Protein CutA; RP4570F34

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O60888

Background: CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached complex, suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson’s disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Concentration: 1 mg/mL

Immunogen: Fusion protein of human CUTA

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only