CX3CL1 Polyclonal Antibody
Catalogue Numbers: BS60619-50, BS60619-100
Sizes: 50µl, 100µl
Alternative Name: Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1; ed into the following chain:Processed fractalkine; CX3CL1; FKN; NTT; SCYD1
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P78423
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Chemokines are members of a superfamily of inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20-50%
homology in their predicted amino acid sequences and are divided into four
subfamilies. In the subfamily designated C-C or β, the first two cysteines are
adjacent. In the C-X-C or a subfamily, the first two of four cysteine residues
are separated by a single amino acid. C subfamily members, also designated
γ chemokines, lack the first and third cysteine residues of the conserved
motif. Chemokines in these three subfamilies are small, secreted proteins
with molecular weights ranging from 7-15 kDa. Fractalkine, also designated
neurotactin, is the first characterized member of a fourth chemokine subfamily.
Fractalkine contains a novel C-X3-C motif in which the first two cysteines
are separated by three amino acid residues. Fractalkine mRNA has been
detected in brain and heart and is upregulated in microglia and endothelial
cells by inflammatory signals. The protein can exist both as a membranebound
form and as a chemotactic soluble form.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CX3CL1 polyclonal antibody detects endogenous levels of CX3CL1 protein.
Bioworld Molecular Weight: ~ 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of CX3CL1 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 whole cell lysate
Lane 2: NIH-3T3 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human CX3CL1
Conjugate: Unconjugated
Modification: Unmodified