Product Description

CXCL4 Polyclonal Antibody

Sizes: 50μL, 100μL, 200μL

Catalogue Numbers: E-AB-40572-50, E-AB-40572-100, E-AB-40572-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CXCL4

Target Synonym: CXCL4; SCYB4; Platelet factor 4; PF-4

Research Areas: Cancer, Cardiovascular, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P02776

Background: CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT

Concentration: 1mg/mL

Immunogen: Recombinant Human CXCL4 protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Purification Method: Antigen Affinity Purification

Dilution: WB: 1:1000-2000

Calculated MW: 10kDa

Observed MW: 14kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only