CXCR-3 rabbit pAb - ES4007

CXCR-3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4007-50, ES4007-100

Citations, Manuals and MSDS Available upon request.

Background: C-X-C motif chemokine receptor 3 (CXCR3) Homo sapiens This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011],

Alternate Name: CXCR3; GPR9; C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse; Pig; Chicken

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CXCR3. AA range:161-210

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 37kD

Human Gene ID: 2833

Human SWISS Prot NO: P49682

Subcellular Location: [Isoform 1]: Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Cell membrane; Multi-pass membrane protein.

Research Use Only