Product Description

CXCR3-B Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A25216-20, A25216-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) .

Category: Polyclonal Antibodies

Applications: WB, IF-P, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 45kDa

Observed Molecular Weight: 43kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 2833

SWISS: P49682-2

Alternate Names: GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; CXCR3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience, Calcium Signaling, Cardiovascular.

NCBI Alias: CXCR3-B

Research Use Only