CXCR4 Rabbit Monoclonal Antibody-BS40124

CXCR4 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40124-50, BS40124-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P61073

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC, ICC/IF

All Applications: WB 1:100~1:200 IHC 1:50~1:200 ICC/IF 1:50~1:200

Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CXCR4 Antibody detects endogenous levels of total CXCR4

Bioworld Molecular Weight: 43kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CXCR4 expression in Jurkat cell lysate., Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, using CXCR4 Antibody., Immunofluorescent analysis of Jurkat cells, using CXCR4 Antibody.

Alternative Name: CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;

Immunogen: A synthesized peptide derived from human CXCR4

Conjugate: Unconjugated

Modification: Unmodified