CXCR4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1303-20, A1303-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 40kDa
Observed Molecular Weight: 36kDa/70kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7852
SWISS: P61073
Alternate Names: FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; WHIMS1; D2S201E; CXCR4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience, Stem Cells, Hematopoietic Progenitors, Neural Stem Cells, Cardiovascular, Angiogenesis.
NCBI Alias: CXCR4
Research Use Only