Product Description

CXCR7 (A356) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2694-50, BS2694-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Members of the C-X-C or α chemokine family are characterized by a pair of cysteine residues separated by a single amino acid and primarily function as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins and include proteins such as IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). C-X-C chemokine receptor type 7 (CXCR-7), also known as RDC-1, is a 362 amino acid receptor for SDF-1. Initially identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor. CXCR-7, with CSCR-4, also acts as a co receptor for human immunodeficiency viruses (HIV). Highly expressed in monocytes, B cells and basophils, and highly active in various biological processes, including cell growth, cell adhesion and tumor growth, CXCR-7 may play a role in tumorigenesis.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, RDC-1, CXCR 7, CMKOR1, GPR159, RDC1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 325-375 of Human CXCR7.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CXCR7 (A356) polyclonal antibody detects endogenous levels of CXCR7 protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P25106

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only