Cyclin E2 Monoclonal Antibody-MB10789

Cyclin E2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10789-50, MB10789-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O96020

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cyclin E2 in Jurkat lysates using Cyclin E2 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cyclin E2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of Cyclin E2 in MCF-7 using Cyclin E2 antibody, and DAPI

Alternative Name: CCNE2; G1/S-specific cyclin-E2

Immunogen: A synthetic peptide of human Cyclin E2

Conjugate: Unconjugated

Modification: Unmodified