Cyclin H Monoclonal Antibody-MB0018

Cyclin H Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0018-50, MB0018-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P51946

Host: Mouse

Reactivity: Human

Applications: WB, IP,

All Applications: WB: 1:1000
IP: 1:50~1:200

Background: Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of CCNH and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size: 38KDa
Observed band size: 38KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot detection of Cyclin H in Jurkat, K562 and A431 cell lysates using Cyclin H antibody (1:1000 diluted)., Immunoprecipitation analysis of Hela cell lysates using Cyclin H antibody

Alternative Name: Cyclin-H; MO15-associated protein; p34; p37; CCNH

Immunogen: Recombinant full length Human Cyclin H.

Conjugate: Unconjugated

Modification: Unmodified