Cyclooxygenase 2 Monoclonal Antibody-MB10758

Cyclooxygenase 2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10758-50, MB10758-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P35354

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 69 kDa; Observed MW: 74 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of COX2/Cyclooxygenase 2 in A549 lysates using Cyclooxygenase 2 antibody., Western blot analysis of COX2/Cyclooxygenase 2 in 3T3 lysates using COX2/Cyclooxygenase 2 antibody.

Alternative Name: COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

Immunogen: Recombinant protein of human COX2/Cyclooxygenase 2

Conjugate: Unconjugated

Modification: Unmodified