Cyclophilin F (Y121) Polyclonal Antibody-BS1976

Cyclophilin F (Y121) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1976-50, BS1976-100

Sizes: 50µl, 100µl

Swiss-Prot: P30405

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Cyclophilin D (CyP40) is a widely expressed cytoplasmic protein that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Cyclophilin F (CyP3), is also known as PPIF, Cyp-D or Rotamase F, is a 207 amino acid mitochondrial matrix protein involved in the induction of necrotic and apoptotic cell death through the activation of the mitochondrial permeability transition (mPT) pore.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cyclophilin F (Y121) polyclonal antibody detects endogenous levels of Cyclophilin F protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Cyclophilin F (Y121) pAb at 1:1000 dilution
Lane 1: The Kidney tissue lysate of Mouse (40ug)
Lane 1: The Testis tissue lysate of Rat (40ug)
Lane 2: MCF-7 whole cell lysate (40ug)
Lane 3: SK-OVCAR3 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Cyclophilin F (Y121) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Peptidyl-prolyl cis-trans isomerase F, mitochondrial; PPIase F; Cyclophilin D; CyP-D; CypD; Cyclophilin F; Mitochondrial cyclophilin; CyP-M; Rotamase F; PPIF; CYP3

Immunogen: Synthetic peptide, corresponding to amino acids 91-140 of Human Cyclophilin F.

Conjugate: Unconjugated

Modification: Unmodified