CYCS Polyclonal Antibody - E-AB-70033

CYCS Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70033-60, E-AB-70033-120, E-AB-70033-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CYCS

Target Synonym: Cytochrome C; Somatic; CYC; Cytochrome C; THC4; HCS.

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P99999,P62898,P62897

Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Concentration: 1.5 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:500-1:1000, IF 1:200-1:800

Calculated MW: 12kDa

Observed MW: 12kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only