CYP11A1 rabbit pAb - ES4947

CYP11A1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4947-50, ES4947-100

Citations, Manuals and MSDS Available upon request.

Background: cytochrome P450 family 11 subfamily A member 1 (CYP11A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008],

Alternate Name: CYP11A1; CYP11A; Cholesterol side-chain cleavage enzyme; mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450 (scc)

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human

Immunogen: The antiserum was produced against synthesized peptide derived from human Cytochrome P450 11A1. AA range:412-461

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 1583

Human SWISS Prot NO: P05108

Subcellular Location: Mitochondrion inner membrane; Peripheral membrane protein. Localizes to the matrix side of the mitochondrion inner membrane.

Research Use Only