Product Description

CYP26C1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61083-50, BS61083-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regμlator of blood pressure) and epoxyeicosatrienoic acid (a molecμle involved in signaling events). CYP26C1 (cytochrome P450, family 26, subfamily C, polypeptide 1) is a 522 amino acid single-pass membrane protein expressed in most tissues at very low levels. Belonging to the cytochrome P450 family, CYP26C1 uses heme groups as cofactors and is induced by retinoic acid. CYP26C1 participates in the retinoic metabolism and acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer, 9-cis-RA.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Cytochrome P450 26C1 (EC:1.14.-.-), CYP26C1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CYP26C1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CYP26C1 polyclonal antibody detects endogenous levels of CYP26C1 protein.

Molecular Weight: ~ 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6V0L0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only