Product Description

CYP27C1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60621-50, BS60621-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regμlator of blood pressure) and epoxyeicosatrienoic acid (a molecμle involved in signaling events). CYP27C1 (cytochrome P450, family 27, subfamily C, polypeptide 1) is a 372 amino acid membrane protein belonging to the cytochrome P450 family. CYP27C1 uses heme groups as cofactors and is encoded by a gene located on human chromosome 2, which consists of 237 million bases, encodes over 1, 400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Cytochrome P450 27C1, CYP27C1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CYP27C1

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CYP27C1 polyclonal antibody detects endogenous levels of CYP27C1 protein.

Molecular Weight: ~ 43 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q4G0S4

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only