Product Description

CYP2B6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS72050-50, BS72050-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CYP2B6 (cytochrome P450 2B6) is a 491 amino acid protein encoded by the human gene CYP2B6. CYP genes are highly polymorphic and can affect individual drug response and adverse reactions to a great extent. The CYP2B6 gene product, along with a few other CYP gene products, are highly susceptible to variation due to several copy number variants (CNV), missense mutations, insertions and deletions, and gene expression mutations. There are 57 active CYP genes and 58 pseudogenes known in the human genome. In liver microsomes, CYP2B6 is involved in an NADPH-dependent electron transport pathway. It acts to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. CYP2B6 is expressed in liver, lung and heart and can be induced by phenobarbital.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA, IHC, IF

Alternate Names: 11B1, CP2B6_HUMAN, CPB 6, CPB6, CYP 2B6, CYP IIB6, CYP2B, CYP2B6, CYP2B7, CYP2B7P, CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 family 2 subfamily B, Cytochrome P450 family 2 subfamily B polypeptide 6, Cytochrome P450 IIB1, Cytochrome P450 phenobarbital inducible, Cytochrome P450 subfamily IIB (phenobarbital inducible), Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6, Cytochrome P450 subfamily IIB polypeptide 6, 1, 4-cineole 2-exo-monooxygenase, IIB1, P450, P450 IIB1, P450IIB1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Cytochrome P450 2B6:401-491/491

Dilution: WB 1:500-2000
ELISA 1:5000-10000
IHC 1:100-500
IF 1:100-500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CYP2B6 polyclonal antibody detects endogenous levels of CYP2B6 protein.

Molecular Weight: ~ 56 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P20813

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only