Product Description

CYP2B6 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23980-50, RA23980-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cytochrome P450 family 2 subfamily B member 6 (CYP2B6) Homo sapiens This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF/ICC, ELISA

Alternate Names: CYP2B6, Cytochrome P450 2B6, 1, 4-cineole 2-exo-monooxygenase, CYPIIB6, Cytochrome P450 IIB1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 56

Protein Molecular Weight (kDa): 56

Storage: -20°C/1 year

Human Gene ID: 1555

Human SwissProt Number: P20813

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only