Product Description

CYP2C9 Polyclonal Antibody

Catalogue Numbers: BS60309-50, BS60309-100

Sizes: 50µl, 100µl

Alternative Name: Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase; CYP2C9; CYP2C10;

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P11712

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Cytochrome P450, family 2, subfamily C polypeptides 9 and 19 are part of the CYP2C subfamily and are responsible for metabolizing many important drugs. CYP2C19 accounts for about 20% of the cytochrome p450 in adult liver. CYP2C9 contributes to the metabolism of fatty acids, prostanoids, and steroid hormones, and it may catalyze potentially toxic bioactivation reactions. A significant negative correlation (r = -0.572, P <.01) between enzyme activity and age was observed for CYP2C19, but there were no sex differences.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CYP2C9 polyclonal antibody detects endogenous levels of CYP2C9 protein.

Bioworld Molecular Weight: ~ 56 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CYP2C9 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: PC12 cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human CYP2C9.

Conjugate: Unconjugated

Modification: Unmodified