Product Description

CYP3A7 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62705-60, E-AB-62705-120, E-AB-62705-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CYP3A7

Target Synonym: CYP3A7; CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA

Research Areas: Cardiovascular,Metabolism,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P24462

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human CYP3A7

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 57kDa/61kDa

Observed MW: 75kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only