CYSLTR1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1815-20, A1815-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 39kDa
Observed Molecular Weight: 38kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 10800
SWISS: Q9Y271
Alternate Names: CYSLT1; CYSLTR; CYSLT1R; HMTMF81; CYSLTR1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Neuroscience.
NCBI Alias: CYSLTR1
Research Use Only