Cystatin C (7F11) Mouse mAb - EM1275

Cystatin C (7F11) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1275-50, EM1275-100

Citations, Manuals and MSDS Available upon request.

Background: Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

Alternate Name: AD8, Cystatin3, Gamma trace, HCCAA

Source: Mouse

Applications: WB, IHC, ELISA

Dilution: WB  1:1, 000-2, 000 IHC 1:100-200  ELISA  1:10, 000-20, 000

Reactivity: Human

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 14kDa

Human Gene ID: 1471

Human SWISS Prot NO: P01034

Subcellular Location: Secreted

Research Use Only