Cystatin E/M rabbit pAb - ES4876

Cystatin E/M rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4876-50, ES4876-100

Citations, Manuals and MSDS Available upon request.

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype. [provided by RefSeq, Jul 2008],

Alternate Name: CST6; Cystatin-M; Cystatin-6; Cystatin-E

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from the Internal region of human Cystatin E/M.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1474

Human SWISS Prot NO: Q15828

Subcellular Location: Secreted

Research Use Only